OneSkin: Reversing Skin Aging From the Cellular Level

OneSkin

Joanna D’amato 2025

ONESKIN: REVERSING SKIN AGING FROM THE CELLULAR LEVEL

Aging Skin? Think Cellular Rejuvenation

Common skincare routines revolve around surface fixes—moisturizers, retinol, antioxidants. OneSkin flips the script by targeting aging at its source: the senescent cells. They disrupt tissue regeneration, drive inflammation, and accelerate visible aging. By addressing these cells directly, OneSkin unlocks a new paradigm in skin longevity.

The Power of Senolytics: Targeting Aging at the Source

Senescent cells are aged cells that refuse to die, emitting inflammatory signals that weaken tissue health. Rather than masking lines or dryness, OneSkin leverages senolytic research—compounds that clear these damaged cells—promoting healthier regeneration.

Their proprietary OS-01 complex is rooted in peer-reviewed science and includes NR (Nicotinamide Riboside), Urolithin A, NMN, and blueberries. These act in concert to protect against DNA damage, promote cellular repair, and stimulate youthful skin functions.

Why Cellular Approach Matters in Anti‑Aging

Most anti-aging products focus on collagen or melanin turnover—helpful, but superficial. OneSkin’s cellular strategy influences:

• Collagen Fragility: Activated fibroblasts support structural integrity

• Oxidative Damage: Enhanced mitochondrial health shields against environmental stress

• Skin Renewal: Senescent cell clearance improves natural cell turnover, tone, and clarity

This foundational approach offers outcomes that go beyond temporary fixes.

OneSkin’s Clean Science: Minimal Formula, Maximum Impact

OneSkin’s line is purposefully streamlined:

• Collagen-Boosting Complex

• Barrier-Support Formula

• Night Repair Concentrate

Each is formulated without parabens, fillers, or unnecessary additives—ideal for biohackers prioritizing purity and potency. Their products are vegan, cruelty-free, and third-party tested for traceability.

Research & Results: Evidence You Can See

Funded studies show:

• Senolytic treatments improve dermal thickness and elasticity

• Cellular repair compounds correlate with reduced wrinkles and enhanced firmness

User trials from OneSkin’s website share stories of smoother texture, fewer fine lines, and more radiant tone—hallmarks of deeper rejuvenation.

Integrating OneSkin into Your Routine

Ideal users include wellness enthusiasts looking to:

• Complement their anti-aging stack with cellular tools

• Support skin integrity with clean, research-driven compounds

• Level up routines beyond retinol and peptides

Simple steps:

• AM: Apply Barrier-Support under SPF

• PM: Follow with Night Repair post-cleansing

• Weekly: Use the Collagen-Boost complex for added regeneration

No need to overhaul your routine—just upgrade the foundation.

Meet the Founders

OneSkin was co-founded by Dr. Tissa Ponticelli and Josh Logan, experts in stem cell biology and regenerative facial treatments. Their vision? Bridge advanced cellular science with elegant, everyday skincare, delivered in a transparent, evidence-first format.

Why It Stands Out in Skin Longevity

OneSkin is:

• Backed by peer-reviewed science on cellular aging

• Clean and minimalistic, free from unnecessary additives

• Clinically tested with strong consumer feedback

Bridging science and simplicity, suitable for everyday biohackers

Is OneSkin Right for You?

If your wellness journey includes advanced protocols—cold plunge, red light, NAD+, peptide stacks—OneSkin offers skincare that matches. It’s for those who believe skin should be treated as living tissue, not just a surface canvas.

Explore More at OneSkin.co

Learn more about their science-backed formulas, clinical data, and get personalized recommendations tailored to your biology.

Final Thoughts

Surface skincare is easy—skin longevity requires cellular intention. OneSkin translates high-level senolytic science into clean, effective, daily routines. For those serious about aging well from the inside out, it’s a next-level tool.

Featured in Biohack Yourself—Summer 2025 IssueDiscover who’s pushing the edge of wellness each issue. Find your copy at major retailers across North America or online at biohackyourselfmarketing.com.

@oneskin.co

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