OneSkin: Reversing Skin Aging From the Cellular Level
OneSkin
Joanna D’amato
2025
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ONESKIN: REVERSING SKIN AGING FROM THE CELLULAR LEVEL
Aging Skin? Think Cellular Rejuvenation
Common skincare routines revolve around surface fixes—moisturizers, retinol, antioxidants. OneSkin flips the script by targeting aging at its source: the senescent cells. They disrupt tissue regeneration, drive inflammation, and accelerate visible aging. By addressing these cells directly, OneSkin unlocks a new paradigm in skin longevity.
The Power of Senolytics: Targeting Aging at the Source
Senescent cells are aged cells that refuse to die, emitting inflammatory signals that weaken tissue health. Rather than masking lines or dryness, OneSkin leverages senolytic research—compounds that clear these damaged cells—promoting healthier regeneration.
Their proprietary OS-01 complex is rooted in peer-reviewed science and includes NR (Nicotinamide Riboside), Urolithin A, NMN, and blueberries. These act in concert to protect against DNA damage, promote cellular repair, and stimulate youthful skin functions.
Why Cellular Approach Matters in Anti‑Aging
Most anti-aging products focus on collagen or melanin turnover—helpful, but superficial. OneSkin’s cellular strategy influences:
Collagen Fragility: Activated fibroblasts support structural integrity
Oxidative Damage: Enhanced mitochondrial health shields against environmental stress
Skin Renewal: Senescent cell clearance improves natural cell turnover, tone, and clarity
This foundational approach offers outcomes that go beyond temporary fixes.
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OneSkin’s Clean Science: Minimal Formula, Maximum Impact
OneSkin’s line is purposefully streamlined:
Collagen-Boosting Complex
Barrier-Support Formula
Night Repair Concentrate
Each is formulated without parabens, fillers, or unnecessary additives—ideal for biohackers prioritizing purity and potency. Their products are vegan, cruelty-free, and third-party tested for traceability.
Research & Results: Evidence You Can See
Funded studies show:
Senolytic treatments improve dermal thickness and elasticity
Cellular repair compounds correlate with reduced wrinkles and enhanced firmness
User trials from OneSkin’s website share stories of smoother texture, fewer fine lines, and more radiant tone—hallmarks of deeper rejuvenation.
Integrating OneSkin into Your Routine
Ideal users include wellness enthusiasts looking to:
Complement their anti-aging stack with cellular tools
Support skin integrity with clean, research-driven compounds
Level up routines beyond retinol and peptides
Simple steps:
AM: Apply Barrier-Support under SPF
PM: Follow with Night Repair post-cleansing
Weekly: Use the Collagen-Boost complex for added regeneration
No need to overhaul your routine—just upgrade the foundation.
Meet the Founders
OneSkin was co-founded by Dr. Tissa Ponticelli and Josh Logan, experts in stem cell biology and regenerative facial treatments. Their vision? Bridge advanced cellular science with elegant, everyday skincare, delivered in a transparent, evidence-first format.
Why It Stands Out in Skin Longevity
OneSkin is:
Backed by peer-reviewed science on cellular aging
Clean and minimalistic, free from unnecessary additives
Clinically tested with strong consumer feedback
Bridging science and simplicity, suitable for everyday biohackers
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Is OneSkin Right for You?
If your wellness journey includes advanced protocols—cold plunge, red light, NAD+, peptide stacks—OneSkin offers skincare that matches. It’s for those who believe skin should be treated as living tissue, not just a surface canvas.
Explore More at OneSkin.co
Learn more about their science-backed formulas, clinical data, and get personalized recommendations tailored to your biology.
Final Thoughts
Surface skincare is easy—skin longevity requires cellular intention. OneSkin translates high-level senolytic science into clean, effective, daily routines. For those serious about aging well from the inside out, it’s a next-level tool.
Featured in Biohack Yourself—Summer 2025 Issue
Discover who’s pushing the edge of wellness each issue. Find your copy at major retailers across North America or online at biohackyourselfmarketing.com.
Disclaimer:
Biohack Yourself Peer Review is an editorial, educational, and entertainment process for sponsored content. It is not a scientific peer review or regulatory evaluation. Please review our full Terms & Conditions and Legal Disclaimers
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