Study Links Linoleic Acid in Seed Oils to Growth of Aggressive Breast Cancer Subtype

Researchers have consistenly warned about the negative affects of seed and vegetable oils on the body, because they cause an inflammatory response.

According to a study conducted by Weill Cornell Medicine, a component of these oils called linoleic acid is linked to the multiplying breast cancer (TNBC) cells, only in triple negative subtypes. TNBC is an aggressive form of breast cancer, the DailMaily.co.uk shared. Because of this it may require intensive treatment like chemotherapy.

With this being true, researchers wanted to dive deeper into this issue. Taking a closer took at the omega-6 fatty acid linoleic acid, this is a nutrient that has what is considered essential for the human body.

Linoleic acid is defined by Weill Cornell Medicine as "an omega-6 fatty acid found in seed oils such as soybean and sunflower oil, and animal products including pork and eggs." However, the Western diet with ultra procedded and fried foods, raises concern on how disease like obesity and cancer rates are increasing.

The study states that "A key initial finding was that linoleic acid does indeed activate mTORC1 in cell and animal models of breast cancers, but only in triple-negative subtypes. (The term “triple negative” refers to the absence of three receptors, including estrogen receptors, that are often expressed by breast tumor cells and can be targeted with specific treatments.)The scientists discovered that this subtype-specific effect occurs because the polyunsaturated fatty acid forms a complex with FABP5, which is produced at high levels in triple-negative breast tumors but not in other subtypes, leading to the assembly and activation of mTORC1, a major regulator of cell metabolism and cancer cell growth."

Dr. John Blenis, the senior author shares, “This discovery helps clarify the relationship between dietary fats and cancer, and sheds light on how to define which patients might benefit the most from specific nutritional recommendations in a personalized manner.”

“We now know that linoleic acid feeds cancer cell growth in a very specific way." he continues, that it "sheds light on how to define which patients might benefit from specific nutritional recommendations.”

Now we are left with the question, what is the best way to avoid breast cancer? Dr. Blenis says “A balanced, whole-food diet remains an important cornerstone of cancer prevention, and a strategy everyone can adopt."

Weill Cornell Medicine says, scientisits will continue to study what linoleic acid can do to the body, and continue to understand how to prevent breast cancer and other diseases.

For more health and wellness news, subscribe to our newsletter here!

Disclaimer:

The information provided here is for entertainment and educational purposes only. It is not intended to substitute medical professional advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Visit the disclaimer link for more details: www.biohackyourself.com/termsanddisclaimers.