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Hacking Biological Information – From Wearables to Artificial Intelligence (AI)

Biohacking Wellness Part II

Dr. Marc Cohen

2024

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Knowledge is power and while biohacking is not new, modern technology and advanced scientific understanding of biological and molecular processes has given biohackers new tools to fulfill the ancient Greek desire to “know thyself”. In the 70s and 80s I toyed with biofeedback devices that measured heart rate and galvanic skin response, and I in the 1990s these gave way to the ECG and EEG machines I used clinically and for bioelectronics research.


Biometric devices now include a plethora of sophisticated wearables that fit elegantly inside jewelry. Devices such the Ouraring, Fitbit and Apple Watch along with specialised sensors such as Xtrodes and neuroimaging companies such as Kernel are revolutionizing the human-machine interface. Biohackers, Lifeloggers and members of the Quantified-Self and Quantified Baby movement can now record a vast array of data including their physical activity, posture, body composition, caloric intake, sleep quality, blood pressure, heart rate variability, blood oxygen saturation, brain waves, blood glucose, ketone levels and other internal processes with relatively inexpensive consumer electronic devices.

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New developments in sensor, battery and signal processing technologies have pushed this technology even further and led to the development of ‘smart-pills’ that wirelessly transmit biometric data and I’ve personally used smart pill temperature sensors in research on temperature regulation in Formula One drivers and was impressed by thei reliability and ease of use. These ingestible sensors, which can also include cameras, patches, and trackers, enable the non-invasive gathering of internal body images and physiological parameters such as pH, pressure, and core temperature, as well as monitoring electrolytes, enzymes, metabolites, hormones, and microbial communities throughout the gut. The field of smart pills is still in its early stages, yet ingestible sensors have the potential to vastly expand our understanding of the gut and revolutionise clinical diagnostics and monitoring to include sampling, biopsies, tissue penetration, targeted drug delivery and personalised diets. This is predicted to expand the smart pill technology market from $3.2 billion in 2020 to $7.5 billion by 2030.


In addition to data from wearable and ingestible biosensors, individual biohackers can now access modern laboratories and have their blood, urine, faeces, hair, sweat, saliva, skin and sperm analysed, and explore their nutritional status, toxic load, microbial diversity and genetics. Modern diagnostic imaging extends this even further by making information from CT scans, MRIs and ultrasound accessible to those who can afford it.


We are entering a brave new world of medical data and doctors are no longer the sole gatekeepers of medical information and biotechnology research is no longer limited to esteemed universities, Big Pharma or well-funded biotech companies. Home hobbyists and citizen-scientists now have more information at their disposal than the most sophisticated and well-funded laboratories and research institutes only a decade or so earlier. In addition, many laboratories and hospitals now give consumers direct access to the results of their tests results, and this empowers consumers to take control of their own health and demand even more information. Access to powerful collaboration tools and sharing platforms that integrate with the blockchain, cloud computing and AI further amplify this power and allow biohackers to conduct experiments on themselves and analyse, compare, and share their data along with their protocols, equipment designs and experiences.

Dr. Marc Cohen

Wellness Consultant & Biohacker

Artificial Intelligence (AI)

Perhaps the most significant technological driver for accessing, analysing and manipulating biological information is the maturing of Artificial Intelligence (AI). We have reached an age when AI can match or exceed the skill of humans who have spent a lifetime mastering their craft. AI has already exceeded some human capabilities and is learning at an increasing rate. In 1997 an AI program beat the world chess champion and we have since seen AI beat human champions at Alphago, Texas Hold’em Poker and Rubiks cube. In 2017 DeepMind, a subsidiary of Google, released AlphaZero, which is an AI program that beat all previous chess programs after only a few hours of ‘self-training’. Deep learning networks are also solving previously intractable problems with Alphafold and ESMFold recently solved the problem of protein folding, and programs such as Chat GPT and other Large Language Models are pushing the boundaries of natural language processing and constantly improving while generating 4.5 billion words a day and forcing universities to reconsider student assessments.


AI can now perceive and do many things that humans simply can’t, and AI can do them much cheaper, faster, and more consistently. While AI cannot yet do everything humans can, it is certainly catching up at an astonishing pace. AI can already compose pop music and symphonies and is touted to replace human artists as well as radiologists and pathologists. It is likely AI will soon exceed skilled humans in diagnostics and clinical care and AI-enabled smartphone apps and medical voice assistants have the potential to make expert medical care available to everyone on earth at very little cost. While we’re yet to see AI used in routine medical care, this time is fast approaching, and the global AI healthcare market is expected to grow at a compound annual growth rate of 38.4% to reach more than US$ 208 Billion in 2030.

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The application of AI and advanced diagnostics are being leveraged by med-tech start-ups such as Fountain Life, which was founded by serial entrepreneurs Tony Robbins and Dr Peter Diamandis (author of Peter’s Laws mentioned above) to develop precision diagnostics and regenerative medicine technologies and implement proactive care that can “find illnesses earlier than ever before to prevent progression and possibly eliminate disease completely”.


The loop between information acquisition and practical interventions is also closing and fitness trackers and smart medical devices can now personalize your Peloton, Technogym or other ‘smart gym’ equipment, while EEG signals can control neurofeedback devices. There are also biofeedback devices such as NuCalm that use biosignals to regulate music and help lower stress, improve concentration, accelerate recovery and enhance sleep. The market for wifi-enabled and other smart devices that make up the Global Internet of Medical Things (IoMT), is currently growing at an annual rate of 23.9% and is expected to reach US$ USD 270.40 billion by 2029.


An unwritten rule in computer systems engineering says “channels get filled with noise because there is always more bandwidth than interesting things to say”. This may simply be a consequence of entropy and the Second Law of Thermodynamics, yet it also means there is generally more hardware, equipment, and facilities for manipulating our inner and outer environments than software to control it or personalise it to our specific needs. Yet AI, deep learning, and sensor-less sensing are stepping in to close this gap.

Realising Worldwide Wellness

With Dr. Marc Cohen

AI DJs can already generate music in real time that adapt to all kinds of moods and environments including a crowd’s reaction. Furthermore, a new range of AI-assisted real-time biofeedback devices are being developed to control temperature, pressure, colour, sound, smell and pulsed electromagnetic stimulation and it won’t be long before AI creates personalised immersive games, narrative videos and augmented reality worlds that engage all our senses and take us on journeys to bring us the greatest enjoyment and transformative healing.


Where this will end lies at the other side of the singularity. Many informed pundits proclaim, super-intelligent AI could be a disaster and that we may be heading towards a dystopian world without humans or where humans are subjugated by AI-powered overlords. Yet, I choose to be optimistic and believe that AI will prefer a world filled with healthy happy humans over a world where humans are diminished or enslaved. We may therefore be heading towards a world where humans are upgraded with superpowers and have super powerful AI friends that serve as our personal gods that can come to know us with infinite patience, interest, wisdom, and love.


Looking Ahead: The Future of Biohacking and Wellness


This is just the beginning of our exploration into the fascinating world of biohacking. Over the coming months, I’ll continue to share insights and practical tools that can help you transform your health and unlock your full potential. Whether you’re looking to optimize your performance, improve longevity, or simply feel better day-to-day, I’m excited to join you on this journey.


About the Author


Dr Marc Cohen is a medical doctor, university professor, author, poet, entrepreneur, wellness trailblazer and perpetual student of life, who believes wellness can be just as contagious as illness. Marc has a deep commitment to promoting accessible wellness practices and aims to co-create a culture of wellness that infects the world with good health. He embodies the role of a bridge-builder, connecting ancient wisdom with modern science, academia with industry, and individual well-being with global health. You can find him at www.drmarc.co

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